Monday, September 27, 2010

Why mundane saline PH is acidic(5.5)?

Why mundane saline PH is acidic(5.5)?
It probably has to do beside carbon dioxide in the heavens. The carbon dioxide dissolves slightly into the saline, and therefore make it a little sharp. Some claim the PVC packaging can contribute as resourcefully. I don't know how well these hypotheses be tested, but they seem to gross sense.
Clinically, it doesn't make a big difference. If you infuse hulking amounts of normal saline into a merciful, you can get a hyperchlorermic metabolic acidosis, but the reason for that aren't related to the starting pH of NS.
To the above poster-- I can't criticize your answer, that's how I would have thought prior to entering tablets. High school and college chemistry would predict a pH of 7.0 exactly as sodium ions and chloride ions are extraordinarily lacklustre bases and acids. Thus, we would expect the pH to resemble the pKa of pure wet, 7.0.
But, reality doesn't other agree with assumption. Take a look at a bag of mundane saline from the hospital. It gives the pH as 5.5 (actually piece of a range). I don't think the manufacturer have broken pH electrodes.
It isn't
Your pH detection method is flawed or your sample is contaminated.
Normal saline is if truth be told more acidic than blood (pH 5.5 or so). Normal blood pH is 7.35-7.45. The drive that it is given is by tradition. Sometimes lactated ringers or plasmalyte is given which actually contains some HCO3 (a questionable anion) that causes the pH to be somewhat more physiologic. There is if truth be told a trend in pills toward these fluids for resusitation fliuds for pH reasons. The glum is that plasmalyte contains potassium which could elevate potassium further in the facade of renal failure.

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